Conditioned Place Preference (CPP)

Conditioned Place Preference (CPP) experiment is widely used to evaluate psychotropic drug dependence,

and it is also an effective tool widely used in drug-seeking behaviors. In CPP animals (rats and mice)

were placed in the white observation area of the conditioned place preference box and given

psychodependent drugs (such as morphine), and then observed to move in the black and white areas of the CPP box.

Each time an animal is in the drug administration zone, it will have a positional preference for black and white areas

under the drug’s rewarding effect, and the situation is close related to the drug’s psychiatric dependence.