Startle PPI Test for Rats, Single Cage System

Pre-pulse inhibition of the Startle reflex (PPI) is a phenomenon in which a weak stimulus (sound or light, or air-puff)

suppress the startle response to a subsequent stronger startle stimulus (of the same kind).

The interest in this technique is mainly due to the fact that impairment in PPI is normally linked to a dysfunction

in the sensorimotor mechanism, which has been shown in patients with psychosis, obsessive-compulsive disorders and Huntington’s disease.

The Ugo Basile system can work with pre-pulses and pulse stimuli of several kind (white noise, frequency noise, light, air puff).

A PC software allows for flexible programming of any kind of procedure with randomizations and seamless data capture.

Customizable, complete set up, ready to go. Includes controller, Startle Link-Box, Isolation Cubicles, Stimulating/Recording Platform.

Different enclosures accommodate for different mice sizes and rat holders are available on request.