Thermal Gradient Ring (TGR)

The TGR can clearly discriminates temperature-dependent phenotypes or temperature dependent drug effects.

It records and analyses thermal preference phenotyping in mice. For neuropathic pain studies, peripheral neuropathy,

temperature sensitivity and insensitivity assessment in basic research, phenotyping and drug screening.

The animal is freely moving, its position is tracked by a camera, and no user intervention is required

to gather time spent in each temperature zone (12 zones in duplicate) and many other parameters.

In the TGR mice can freely move around the ring floor, thereby avoiding the stereotypical habit

that mice have of staying in a corner, as occurs in rectangular systems.

It is a cost effective and bias-free tool to obtain reproducible data

in a very broad range of thermal stimulation experiments.