Startle Reflex System

Prepulse inhibition (PPI) is the phenomenon in which a weak prepulse stimulus attenuates the response to a subsequent startling stimulus.

The stimuli are usually acoustic, light and tactile stimuli. Patients with schizophrenia and some other neuropsychiatric disorders have impaired PPI.

Science’s Rodent Startle Reflex System allow for Pre-pulse inhibition and fear-potentiated startle protocols efficiently and economically.

 Animal models are widely used to test hopotheses lining genetic components of various diseases.